Tissue repair and cell growth
Inward growth of neovascularization:
The blood flow of food is necessary to start and maintain the processes of repairing the structure of damaged tissue. The application of acoustic waves creates capillary micro-breaks in the tendon and bone and significantly increases the expression of growth indicators such as eNOS, VEGF, PCNA and BMP.
These two processes stimulate the growth and reshaping of new arterioles. The new blood vessels will improve blood supply and oxygenation resulting in faster healing of the tendon and bone.
Reversal of chronic inflammation:
Chronic inflammation occurs when the inflammation reaction is not completely stopped. It can damage healthy parts of the body and can lead to chronic pain. The activity of mast cells, involved in the inflammatory process, can be increased by insinuating acoustic waves. Mast cell activation can be followed by the synthesis of chemokines and cytokines. Unblocking pro-inflammatory mixtures, if necessary, can help restore normal healing and regenerative processes.
The production of sufficient amounts of collagen is a necessary precondition for the tissue repair process. Shock wave therapy accelerates procollagen synthesis. The newly created collagen fibers are imposed in a longitudinal structure. These newly formed tendon fibers are denser and harder.
Acoustic waves support neovascularization, the production of collagens and restore healing, but they also allow an increase in growth factors, an increase in mesenchymal stem cells and above all a stimulation of metabolism.